The 44-year-old left Southampton to take charge of Spurs in May 2014 and has now agreed fresh terms, tying him to the club until 2021.
After Tottenham finished fifth in his first season, Pochettino will secure a second-place Premier League finish with at least a point in their final match of 2015-16 at Newcastle United.
The ex-Espanyol boss was linked with replacing Louis van Gaal at Manchester United – speculation fuelled by a recent meeting with former Old Trafford manager, and current director, Alex Ferguson – but he has now signed a contract that he announced was agreed last month.
"I could not be happier to sign this new contract," said Pochettino.
"It was an easy decision for my coaching staff and I because we can feel the appreciation of everyone here - there is no better place to be right now.
"The supporters are unbelievable, we have assembled a great group of players with huge potential that can get even better, while the facilities we have to work in are world-class.
"We also have an incredible new stadium to look forward to and now we are determined to build a side worthy of playing in such an exciting new venue.
"We have enjoyed a great season and we believe this is just the beginning. We have a long-term project and huge belief that we can achieve something big here for the future.
"This club has all the ingredients to continue to challenge at the very top in both the Premier League and in Europe and we want to be here to be a part of what I believe will be a special period in the club's history."
